منابع مشابه
P-35: Vitrification Induced Apoptosis in MiceBlastocysts
Background: Apoptosis is induced by several factors and has an important role in embryonic development. Since vitrification-induced embryonic damages could be resulted from an increase in apoptosis occurrence,the aim of the present study is to investigate the effect of vitrification on induction of apoptosis in blastocysts. Materials and Methods: For this purpose 20 balb-c mice superovulated an...
متن کاملAntiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Infected Cell
Citation: Xu J, Li X, Jiang B, Feng X, Wu J, Cai Y, Zhang X, Huang X, Sealy JE, Iqbal M and Li Y (2018) Antiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Infected Cell. Front. Microbiol. 9:653. doi: 10.3389/fmicb.2018.00653 Antiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Inf...
متن کاملRecombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells
BACKGROUND Our study aims to evaluate the anti-growth effects of recombinant immunotoxin (IT) anti-c-Met/PE38KDEL on gastric cancer cells, and its mechnisms. METHODS Gastric cancer cells were treated with increasing doses of IT and c-Met protein was quantified by Western blotting. Cell proliferation was determined by Cell Counting Kit-8 assay (CCK). [3H]-leucine incorporation assay was used t...
متن کاملThe novel immunotoxin HM1.24-ETA′ induces apoptosis in multiple myeloma cells
Despite new treatment modalities, the clinical outcome in a substantial number of patients with multiple myeloma (MM) has yet to be improved. Antibody-based targeted therapies for myeloma patients could make use of the HM1.24 antigen (CD317), a surface molecule overexpressed on malignant plasma cells and efficiently internalized. Here, a novel immunotoxin, HM1.24-ETA', is described. HM1.24-ETA'...
متن کاملOleuropein Attenuates Deltamethrin-induced Apoptosis in Rat Cerebellar Purkinje Neurons
Background: Deltamethrin (DM) is a synthetic pyrethroid insecticide that can elicit neurotoxicity, and lead to apoptosis. There is accumulating evidence that oleuropein (OE) has anti-apoptotic effect. This study aimed at determining the DM toxicity and anti-apoptotic effect of OE pretreatment in cerebellar Purkinje neurons. Materials and Methods: Rats were randomly divided into four groups a...
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ژورنال
عنوان ژورنال: Stem Cells
سال: 2000
ISSN: 1066-5099,1549-4918
DOI: 10.1634/stemcells.18-5-384